Ceramide and Reishi Serum – the key to strong skin

Have you heard about Ceramide Serum and Reishi? It's a cosmic combination! Do you know why ceramides are crucial for skin health? I'll try to explain it to you.

CERAMIDES - WHAT ARE THEY?

Ceramides , natural lipids, are an essential part of our skin, where they play an important role in its hydration and elasticity. These key ingredients are found in Orientana's highly rated serum , where they create a protective barrier for the skin.

Ceramides are bioactive lipids belonging to the sphingolipid group, which play a key role in maintaining the integrity and function of the epidermal barrier. They constitute about 50% of the lipids of the stratum corneum, where – alongside cholesterol and free fatty acids – they create an ordered lipid structure responsible for limiting transepidermal water loss (TEWL) and protecting the skin from external factors. Ceramides act as an “intercellular cement”, bonding corneocytes and ensuring proper tightness of the epidermis.

Keratinocytes are the builders of the skin

Keratinocytes are directly related to ceramides , because they are the ones that produce ceramides – key lipids responsible for the proper functioning of the epidermal barrier. They can be described as a ceramide factory. Keratinocytes constitute the main population of epidermal cells (epidermis), accounting for about 90–95% of all its cells. They are specialized epithelial cells that play a key role in the formation, maintenance and regeneration of the skin's protective barrier. Their primary function is the production of keratin – a structural protein that provides the skin with mechanical strength and resistance to external factors.

The life cycle of keratinocytes begins in the basal layer (stratum basale), where these cells proliferate intensively. Then they move to the surface of the epidermis, passing through successive layers: the spinous layer (stratum spinosum), the granular layer (stratum granulosum), and finally the stratum corneum (stratum corneum). In this process, keratinocytes undergo gradual terminal differentiation, losing their cell nuclei and transforming into corneocytes – “dead” horny cells that form the outer, protective covering of the skin. The entire cycle from proliferation to desquamation takes about 28 days in a healthy adult.

During their migration to the surface, keratinocytes synthesize not only keratin, but also a number of structural proteins and enzymes (e.g. filaggrin, loricrin, involucrin), which form the so-called corneocyte envelope – an integral part of the physical skin barrier. At the same time, they produce intercellular lipids, such as ceramides, cholesterol and free fatty acids, which cement cells in the stratum corneum, ensuring tightness and limiting transepidermal water loss (TEWL).

Keratinocytes also play an important immunological role. In response to mechanical damage, UV radiation or the presence of pathogens, they release cytokines, chemokines and antimicrobial peptides (including defensins and cathelicidins), activating a local inflammatory response and communicating with immune system cells. As a result, they are not only a physical barrier, but also an active participant in the skin's immunological defense.

Mechanisms of action of ceramides at the cellular level

From the perspective of skin biology, ceramides not only play a structural role, but also demonstrate signaling activity. They participate in the processes of keratinocyte differentiation and regulation of the inflammatory response. Studies have shown that their deficiency leads to skin barrier dysfunction, which is manifested by increased TEWL, dryness, itching, and increased susceptibility to irritants and allergens. Reduced levels of ceramides are observed in dermatological diseases such as atopic dermatitis, psoriasis, and eczema.

Ceramides in cosmetology and aesthetic dermatology

The use of ceramides in dermocosmetic preparations is aimed at rebuilding the lipid barrier and restoring epidermal homeostasis. These ingredients demonstrate high biocompatibility, which is why they can also be used in products intended for sensitive and reactive skin. A study conducted by Sugarman et al. (2005) showed that the use of an emulsion containing ceramides type 1, 3 and 6-II for 4 weeks significantly reduced TEWL and improved skin hydration parameters in a group of patients with AD.

Ceramides and reishi serum - protection of the hydrolipid barrier

The proper condition of the skin's hydrolipid barrier is extremely important to protect it from water loss and protect it from harmful external factors, such as free radicals, toxins, environmental pollution, and bacteria. Have you wondered how to protect this barrier? Do you know what the symptoms of its destruction are?

Symptoms of damage to this barrier are usually easy to spot. The skin becomes dry, rough and flaky, and there is often a feeling of tightness, burning or itching. There may also be redness and hyperreactivity – the skin reacts with irritation even to mild cosmetics or water. In more advanced cases, there are micro-cracks in the epidermis, inflammation and even severe symptoms of dermatological diseases such as atopic dermatitis or rosacea.

Ceramides and reishi serum - The role of ceramides in skin care

Ceramides are an invaluable ingredient in the process of rebuilding the skin barrier. Their ability to increase keratinocyte cell adhesion leads to stronger cell bonding, which results in the creation of a strong skin structure. Therefore, ceramides are irreplaceable in the care of dry, sensitive skin, and as support during retinoid or acid treatment.

That is why we recommend using Ceramide and Reishi Serum during the day and retinol cosmetics at night.

With age, a physiological decrease in ceramide synthesis is observed in the epidermis, which results in a weakening of the barrier function and an increase in the symptoms of dryness, roughness and loss of elasticity. Cosmetics enriched with ceramides can compensate for these deficiencies, supporting regenerative processes and improving the overall condition of mature skin. Thanks to this, ceramides are an important element of a care strategy aimed at rebuilding and protecting the skin barrier.

Ceramides and reishi serum - the role of adaptogen in skin care

Reishi (Ganoderma lucidum), also known as Ganoderma lucidum, is a mushroom with unique adaptogenic properties that has been used in Chinese medicine for over 2,000 years. Its effects include immune support, anti-inflammatory action and modulation of oxidative stress – factors that are also key to skin health. In recent years, reishi has gained popularity as a cosmetic ingredient with a broad spectrum of biological action. Orientana uses this ingredient in a series of facial cosmetics.

Reishi supports the balance of the skin microbiome and limits excessive immune response, which may be important in the context of atopic, acne or psoriasis skin care. Regular use of cosmetics with its content contributes to improving the elasticity, hydration and overall resistance of the skin to external stressors.

Additionally, thanks to the presence of natural antioxidants, reishi helps protect against photoaging and has a rejuvenating effect on the skin.

How to choose cosmetics with ceramides?

Ceramide Reishi Serum demonstrates exceptional biocompatibility with the skin, enabling deep penetration of ceramide NP into the epidermis. As a result, it works very effectively on rebuilding the hydrolipid barrier, improves skin elasticity and firmness, and also reduces the visibility of wrinkles.

When choosing cosmetics with ceramides, it is important to pay attention to their composition and biocompatibility with ceramides naturally occurring in the skin. Products such as Orientana Ceramides Reishi serum are pioneers in skin care, offering the highest quality and effectiveness in rebuilding the skin barrier.

Orientana is a brand that guarantees the quality and effectiveness of its products, using the latest scientific achievements in dermatology and cosmetology, using natural plant ingredients sourced directly from ecologically clean regions of Asia. The right selection of cosmetics with ceramides is the key to healthy, firm and strong skin.