Retinol is the undisputed king of anti-aging ingredients, but its traditional form brings with it a number of problems: irritation, photosensitivity, instability, and limited skin tolerance.
Biotechnology offers a revolutionary solution to these problems in the form of Novo-Retin - a new-generation biotechnological retinol, also known as bioretinol or phytoretinol.
Table of Contents:
- Introduction - retinol and the challenges of classic formulas
- What is NovoRetin™ bioretinol?
- Mechanism of action of bioretinol
- Why did Orientana choose NovoRetin™ in an eye cream?
- Advantages of bioretinol vs. traditional retinol
- Clinical effects and efficacy of NovoRetin™
- Safety and skin tolerance
- The future of biotechnological retinoids
- Summary - NovoRetin™ as a new era of retinol in anti-aging skincare
Why did Orientana use bioretinol in its anti-wrinkle eye cream?
Lower risk of irritation and peeling
Stability and possibility of use during the day / in brighter conditions
Anti-aging and firming effects
Moisturizing effects
Less photosensitivity
Multidirectional action
What is NovoRetin™ Bioretinol?
NovoRetin™ is an innovative raw ingredient - bioretinol, which increases the amount of naturally occurring retinoic acid in the skin, leading to retinol-like effects.
Bioretinol creation process:
- Raw material basis: Mastic is used - an aromatic resin produced by the mastic tree (Pistacia lentiscus), which has been valued for its therapeutic and skincare properties since ancient times.
- Innovative bioavailability system: A unique system for delivering the ingredient to the skin has been developed, making bioretinol bioavailable to the skin.
- Water-soluble process: Thanks to the technology used, a water-soluble product is created, which eliminates previous problems with formulating cosmetics containing mastic.
- Final effect: NovoRetin™ is easy to formulate and offers an innovative alternative to retinol in skincare preparations, as it enhances the level of naturally occurring retinoids in the skin.
Mechanism of action of bioretinol
Novo-Retin acts on the same receptors as traditional retinol (RAR and RXR receptors), but in a much gentler and more controlled manner. Instead of "bombarding" the skin with high concentrations of active substance, biotechnological retinol is released gradually, allowing the skin to adapt to its action.
The key difference lies in the activation method. Traditional retinol must be converted by skin enzymes into retinoic acid - its active form. This conversion process often leads to irritation and unpredictable reactions. Novo-Retin already contains ready precursors that are gently released and activated in response to the skin's needs.
Cellular action includes:
- Stimulation of cell renewal - accelerating the natural process of epidermal exfoliation
- Increased collagen production - activation of fibroblasts in the dermis
- Sebum production regulation - normalization of sebaceous gland function
- Antioxidant action - protection against free radicals
Advantages of bioretinol used in Orientana eye cream compared to traditional retinol
Elimination of retinoid dermatitis
This is the greatest advantage of biotechnological retinol. Novo-Retin does not cause the characteristic "retinol burn" - redness, peeling, and irritation that often accompany the use of traditional retinoids.
Lack of photosensitivity
This means that Novo-Retin can also be used during the day, unlike classic retinol, which increases skin sensitivity to UV radiation. This is a revolutionary change that greatly facilitates the inclusion of retinol in daily skincare routines.
Stability in formula
This is another key advantage. Traditional retinol is extremely unstable - it breaks down under the influence of light, air, and heat. Novo-Retin maintains its activity for a much longer time, which translates into greater effectiveness of the final products.
Compatibility with other ingredients
Compatibility with other ingredients is significantly better. Novo-Retin can be safely combined with vitamin C or AHA/BHA acids - combinations that could be problematic with traditional retinol.
Safety during pregnancy
This is an additional advantage - although it is always advisable to consult a doctor, Novo-Retin does not show the developmental toxicity characteristic of high doses of retinoids.
Clinical studies and efficacy of bioretinol
Comparative studies of Novo-Retin vs. 0.5% retinol conducted on a group of 120 people over 12 weeks showed:
- Wrinkle reduction: Novo-Retin 28% vs. retinol 25%
- Improved elasticity: Novo-Retin 31% vs. retinol 24%
- Reduced discoloration: Novo-Retin 34% vs. retinol 29%
- Skin irritation: Novo-Retin 5% vs. retinol 47%
Long-term safety studies involving 6 months of use showed no adverse side effects, while the group using traditional retinol reported 23% cases of persistent irritation.
Studies on sensitive skin are particularly impressive - 89% of people with sensitive skin tolerated Novo-Retin without any negative reactions, while only 12% could use traditional retinol.
* manufacturer's research
The future of biotechnological retinoids
New generations of bio-retinols are already in the research phase. Scientists are working on molecules that will be even more selective in their action - activating only those receptors responsible for positive anti-aging effects, without affecting those causing irritation.
Personalization of bio-retinols based on genetic analysis will allow for adjusting the type and concentration of biotechnological retinol to individual skin predispositions.
Combinations with other biotechnological ingredients open up possibilities for creating synergistic complexes with multidirectional anti-aging effects.
Novo-Retin represents the future of retinoids in cosmetics - it combines the proven effectiveness of traditional retinol with the safety and comfort of using biotechnological ingredients. This is a solution that we have implemented in our new Anti-aging series as one of the few brands worldwide.
If you are looking for eye creams and serums, check out Eye Area Care.
